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mercredi, octobre 4 2017

Improved Scatter Search Algorithm for Predicting Protein Structures download ebook

Iman Ghalayini: Improved Scatter Search Algorithm for Predicting Protein Structures

Improved Scatter Search Algorithm for Predicting Protein Structures


Description

In this book, I present an improved scatter search (SS) algorithm for predicting all-atoms protein structures using the CHARMM22 energy model. My algorithm produces a 3D structure of the whole protein by minimizing the energy function linked to protein folding. This is based on a sequence of amino acids as well as on data collected from known protein structures for comparative purposes. Defined as an evolutionary algorithm, SS relies on a population of candidate solutions. Candidate solutions, over a number of iterations, experience evolutionary operations which combine intense search and diversification. My algorithm is evaluated on few proteins, whose structure is defined in a Protein Data Bank (PDB). The results generated by the improved SS algorithm are compared with those of other energy models. The results showed that my algorithm produces 3D structures with good and promising root mean square deviations from the reference proteins. This study also demonstrates the advantage of the CHARMM22 energy model.


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Author: Iman Ghalayini
Number of Pages: 72 pages
Published Date: 12 May 2011
Publisher: VDM Verlag
Publication Country: Germany
Language: English
ISBN: 9783639355956
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>FREE< Elocution The sources and elements of its power download epub

Joshua Hall McIlvaine: Elocution The sources and elements of its power

Elocution The sources and elements of its power


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Elocution. The sources and elements of its power. A textbook for schools and colleges, and a book for every public speaker, and student of the English language (1895). This book, "Elocution. The sources and elements of its power", by Joshua Hall McIlvaine, is a replication of a book originally published before 1895. It has been restored by human beings, page by page, so that you may enjoy it in a form as close to the original as possible. This book was created using print-on-demand technology. Thank you for supporting classic literature.


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Author: Joshua Hall McIlvaine
Number of Pages: 422 pages
Published Date: 15 Jul 2013
Publisher: Nobel Press
Publication Country: United Kingdom
Language: English
ISBN: 9785518665637
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*FREE* Protein Networks and Pathway Analysis download pdf

Yuri Nikolsky,Julie Bryant: Protein Networks and Pathway Analysis

Protein Networks and Pathway Analysis


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From the beginning of the OMICs biology era, science has been pursuing the reduction of the complex "genome-wide" assays in order to understand the essential biology that lies beneath it. In Protein Networks and Pathway Analysis, expert practitioners present a compilation of methods of functional data analysis, often referred to as "systems biology," and its applications in drug discovery, medicine and basic disease research. The volume is divided into three convenient sections, covering the elucidation of protein, compound and gene interactions, analytical tools, including networks, interactome and ontologies, and applications of functional analysis. As a volume in the highly successful Methods in Molecular Biology (TM) series, this work provides detailed descriptions and hands-on implementation advice. Authoritative and cutting-edge, Protein Networks and Pathway Analysis presents both "wet lab" experimental methods and computational tools in order to cover a broad spectrum of issues in this fascinating new field.


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Author: Yuri Nikolsky,Julie Bryant
Number of Pages: 410 pages
Published Date: 01 Dec 2011
Publisher: Humana Press Inc.
Publication Country: Totowa, NJ, United States
Language: English
ISBN: 9781617794889
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mercredi, septembre 27 2017

>FREE< Peace download PDF

Gene Wolfe,David Hartwell: Peace

Peace


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Originally published in 1975, Peace is a spellbinding, brilliant tour de force of the imagination. The melancholy memoir of Alden Dennis Weer, an embittered old man living out his last days in a small midwestern town, the novel reveals a miraculous dimension as the narrative unfolds. For Weer's imagination has the power to obliterate time and reshape reality, transcending even death itself. Powerfully moving and uncompromisingly honest, Peace ranks alongside the finest literary works of our time. Hailed as "one of the literary giants of SF" by the Denver Post, Gene Wolfe has repeatedly won the field's highest honors, including the Nebula, the Hugo, and the World Fantasy awards. Peace is Gene Wolfe's first full-length novel, a work that shows the genius that later flourished in such acclaimed works as The Fifth Head of Cerberus and The Book of The New Sun.

The most trusted guide to the world of children's publishing! If you write or illustrate for young readers with the hope of getting published, Children's Writer's & Illustrator's Market 2017 is the trusted resource you need. Now in its 29th edition, CWIM is the definitive publishing guide for anyone who seeks to write or illustrate for kids and young adults. Inside you'll find more than 500 listings for children's books markets (publishers, literary agents, magazines, contests, and Peace free ebook more), including a point of contact, how to properly submit your work, and what categories each market accepts. CWIM also features:* Interviews with accomplished authors and illustrators, such as Victoria Aveyard (Red Queen), Rainbow Rowell (Eleanor & Park), Judy Schachner (the Skippyjon Jones series), and more.* Valuable advice from debut authors and illustrators who explain their personal paths to success and publication.* Informative articles on how to be your own agent, craft a great query letter, avoid picture book pitfalls, discover new online publishing opportunities, and much more.* A one-year subscription to the children's publishing content on WritersMarket.comIncludes exclusive access to the new webinar "Breaking Into Kidlit: Tips for Writing Picture Books, Middle-Grade, and Young Adult" by agent Susan Hawk of The Bent Agency.


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Author: Gene Wolfe,David Hartwell
Number of Pages: 320 pages
Published Date: 14 Jan 2013
Publisher: Starscape
Publication Country: New York, United States
Language: English
ISBN: 9780765334565
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At Home with the Templetons download pdf, epub

Monica McInerney: At Home with the Templetons

At Home with the Templetons


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Other people's families aren't always as perfect as they seem When the Templeton family from England takes up residence in a stately home in country Australia, they set the locals talking -- and with good reason. From the outside, the seven Templetons seem so unusual ...peculiar even. No one is more intrigued by the family than their neighbours, single mother Nina Donovan and her young son Tom. Before long, the two families' lives become entwined in unexpected ways, to the delight of Gracie, the youngest of the Templeton daughters. In the years that follow, the relationships between the Templetons and the two Donovans twist and turn in unpredictable and life-changing directions, until a tragedy tears them all apart. What will it take to bring them together again? From Australia's top-selling female novelist comes her best book yet -- a wonderfully entertaining and touching story about the perils and pleasures of love, friendship and family. 'A modern-day Jane Austen' Sun Herald


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Author: Monica McInerney
Number of Pages: 400 pages
Published Date: 01 Apr 2011
Publisher: Pan MacMillan
Publication Country: London, United Kingdom
Language: English
ISBN: 9780330447836
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[FREE] Yo-Kai Watch, Vol. 3 pdf

Noriyuki Konishi: Yo-Kai Watch, Vol. 3

Yo-Kai Watch, Vol. 3


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Nathan Adams is just an average kid until the mysterious Whisper gives him a device that allows him to see what others cannot, Yo-kai of all shapes and forms! Now, armed with the Yo-kai Watch, Nathan, Whisper and their new invisible friends embark on an all-new supernatural adventure! Yo-kai, inspired by the yokai of Japanese folklore, are not ghosts or monsters or creatures. They can t be seen by the human eye, but they re everywhere, and whether they're phantoms or everyday objects discovering their higher purpose, Yo-kai personalities are distinctly humanlike!"


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Author: Noriyuki Konishi
Number of Pages: 192 pages
Published Date: 05 May 2016
Publisher: Viz Media, Subs. of Shogakukan Inc
Publication Country: San Francisco, United States
Language: English
ISBN: 9781421582733
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mardi, septembre 19 2017

You Shall Know Our Velocity pdf, epub, mobi

Dave Eggers: You Shall Know Our Velocity

You Shall Know Our Velocity


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In his first novel, Dave Eggers has written a moving and hilarious tale of two friends who fly around the world trying to give away a lot of money and free themselves from a profound loss. It reminds us once again what an important, necessary talent Dave Eggers is.

This book will help you: Learn PMP's underlying concepts to help you understand the PMBOK principles and pass the certification exam with flying colors Get 100% coverage of the latest principles and certification objectives in The PMBOK Guide, Fifth Edition Make use of a thorough and effective preparation guide with hundreds of practice questions and exam strategies Explore the material through puzzles, games, problems, and exercises that make learning easy and entertaining Head First PMP puts project management principles into context to help you understand, remember, and apply them - not just on the exam, but also Because of Low pdf on the job. From the bestselling Setting Limits series comes an invaluable guide for parents of strong-willed teenagers that explains how to effectively enforce discipline, encourage healthy growth, and create rewarding relationships with teens.


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Author: Dave Eggers
Number of Pages: 416 pages
Published Date: 01 Jul 2003
Publisher: Knopf Doubleday Publishing Group
Publication Country: New York, NY, United States
Language: English
ISBN: 9781400033546
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*FREE* Because of Low download pdf

Abbi Glines: Because of Low

Because of Low


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It's steamy in the Gulf town of Sea Breeze. Physical attraction is the only way to beat the heat in this second book of the Sea Breeze series from bestselling, previously self-published author Abbi Glines. Playboy Cage owns the apartment, and he hosts a revolving door of people, in and out, at all times. Most of them are long-legged hot girls who are never there more than a night or two. When Cage's new roommate, Marcus, enters the picture, he's just looking to nurse a broken heart. But there's one particular semi-frequent regular who catches his eye. Willow--"Low"--is the one Cage wants to marry. But the two of them are night and day, and Marcus can't see how Low puts up with all of Cage's womanizing. What she really needs is a real man....like good-looking and sensible Marcus. But that's going to get real complicated and real messy--real fast.

This book will help you: Learn PMP's underlying concepts to help you understand the PMBOK principles and pass the certification exam with flying colors Get 100% coverage of the latest principles and certification objectives in The PMBOK Guide, Fifth Edition Make use of a thorough and effective preparation guide with hundreds of practice questions and exam strategies Explore the material through puzzles, games, problems, and exercises that make learning easy and entertaining Head First PMP puts project management principles into context to help you understand, remember, and apply them - not just on the exam, but also Because of Low pdf on the job. From the bestselling Setting Limits series comes an invaluable guide for parents of strong-willed teenagers that explains how to effectively enforce discipline, encourage healthy growth, and create rewarding relationships with teens.


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Author: Abbi Glines
Number of Pages: 290 pages
Published Date: 02 Jul 2013
Publisher: Simon Pulse
Publication Country: New York, United States
Language: English
ISBN: 9781442488632
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Helen Lester,Lynn Munsinger: Tacky in Trouble

Tacky in Trouble


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Tacky the Penguin goes windsurfing and ends up on a tropical island, captive to an elephant who, upon seeing Tacky s floral Hawaiian shirt, mistakes him for a bouquet of flowers. The elephant thinks that Tacky would make a pretty centerpiece, so she arranges him in a vase and sets him on her table. Tacky s fans are sure to delight in the show as Tacky uses all of his best penguin moves to wriggle himself out of this hilarious jungle mix-up. Only the team of Helen Lester and Lynn Munsinger could pull off a tale of such far-fetched adventure. They are masters at the art of creating silly stories and beloved characters that make children laugh out loud."


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Author: Helen Lester,Lynn Munsinger
Number of Pages: 32 pages
Published Date: 31 May 2005
Publisher: Walter Lorraine Books
Publication Country: New York, United States
Language: English
ISBN: 9780618380084
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jeudi, septembre 14 2017

[FREE] Musical Nativity pdf, epub, mobi

Felicity Brooks,Alida Massari: Musical Nativity

Musical Nativity


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This picture book tells timeless tale of Jesus' birth, for young children. Follow Mary and Joseph as they travel by donkey to the stable in Bethlehem, and meet the shepherds and wise men as they follow the star, on their way to give gifts to Baby Jesus. Children will love pressing the buttons to hear the festive music which accompanies each scene.

Newbery Honor winning author Gennifer Choldenko deftly combines humor, tragedy, fascinating historical detail, and a medical mystery in this exuberant new novel. "Physiological Bases of Human Performance during Work and Exercise" is a high-level physiology text for advanced students, researchers and practitioners in the fields of human physiology, exercise science and applied physiology. Eighty internationally recognised scientists from sixteen countries have written chapters within six areas: physiological performance limits and human adaptation; the physiological bases of gender differences in performance; age and human performance; performance under environmental extremes; exercise and health interactions; and, optimising performance through supplementation. Each section contains state-of-the-art reviews of the Musical Nativity download epub scientific literature. To stimulate critical thinking, there are thirteen debates and discussions that focus on some of the controversial topics that exist across these disciplines.


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Author: Felicity Brooks,Alida Massari
Number of Pages: 10 pages
Published Date: 12 Oct 2015
Publisher: Usborne Publishing Ltd
Publication Country: London, United Kingdom
Language: English
ISBN: 9781409597674
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James Luceno: Star Wars: The New Jedi Order - Agents of Chaos - Jedi Eclipse

Star Wars: The New Jedi Order - Agents of Chaos - Jedi Eclipse


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A string of smashing victories by the forces of the sinister aliens known as the Yuuzhan Vong has left New Republic resources and morale stretched to the breaking point. Leia Organa Solo, estranged from her husband, Han, oversees the evacuation of refugees on planets in the path of the merciless invaders. Luke Skywalker struggles to hold the fractious Jedi Knights together, even while one of them undertakes a bold but reckless undercover mission. Manipulating their alliance with the amoral Hutts, the Yuuzhan Vong leave a cunning trail of vital information where New Republic agents are sure to find it-information the desperate defenders cannot afford to ignore: the location of the aliens' next target.Then Han Solo stumbles into the dark heart of a raging battle, thus beginning a furious race against time that will require every skill and trick in his arsenal towin


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Author: James Luceno
Number of Pages: 368 pages
Published Date: 05 Aug 2000
Publisher: Cornerstone
Publication Country: London, United Kingdom
Language: English
ISBN: 9780099410249
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Frederick C. Copleston: A History of Philosophy: Maine de Biran to Sartre v. 9

A History of Philosophy: Maine de Biran to Sartre v. 9


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Conceived originally as a serious presentation of the development of philosophy for Catholic seminary students, Frederick Copleston's nine-volume "A History Of Philosophy" has journeyed far beyond the modest purpose of its author to universal acclaim as the best history of philosophy in English.


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Author: Frederick C. Copleston
Number of Pages: 496 pages
Published Date: 01 Dec 1996
Publisher: Transworld Publishers Ltd
Publication Country: London, United Kingdom
Language: English
ISBN: 9780385470469
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samedi, septembre 2 2017

[FREE] Community: Seeking Safety in an Insecure World pdf, epub, mobi

Zygmunt Bauman: Community: Seeking Safety in an Insecure World

Community: Seeking Safety in an Insecure World


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a Communitya is one of those words that feels good: it is good a to have a communitya , a to be in a communitya . And a communitya feels good because of the meanings which the word conveys, all of them promising pleasures, and more often than not the kind of pleasures which we would like to experience but seem to miss. a Communitya conveys the image of a warm and comfortable place, like a fireplace at which we warm our hands on a frosty day. Out there, in the street, all sorts of dangers lie in ambush; in here, in the community, we can relax and feel safe. a Communitya stands for the kind of world which we long to inhabit but which is not, regrettably, available to us. Today a communitya is another name for paradise lost -- but for a paradise which we still hope to find, as we feverishly search for the roads that may lead us there. But there is a price to be paid for the privilege of being in a community. Community promises security but seems to deprive us of freedom, of the right to be ourselves. Security and freedom are two equally precious and coveted values which could be balanced to some degree, but hardly ever fully reconciled. The tension between security and freedom, and between community and individuality, is unlikely ever to be resolved. We cannot escape the dilemma but we can take stock of the opportunities and the dangers, and at least try to avoid repeating past errors. In this important new book, Zygmunt Bauman takes stock of these opportunities and dangers and, in his distinctive and brilliant fashion, offers a much--needed reappraisal of a concept that has become central to current debates about the nature and future of our societies.


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Author: Zygmunt Bauman
Number of Pages: 168 pages
Published Date: 15 Feb 2001
Publisher: Polity Press
Publication Country: Oxford, United Kingdom
Language: English
ISBN: 9780745626352
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Simona Sanfilippo: Rapunzel

Rapunzel


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Step into the magical world of Child's Play fairy tales...Traditional tales are a well-established part of all cultures. Retold from the originals, these lively stories will captivate readers with their delightful illustrations and fun lift-up flaps which really add to the action. The 'flip-up' flaps encourage prediction and discussion, and well-known stories will give young readers confidence.


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Author: Simona Sanfilippo
Number of Pages: 24 pages
Published Date: 01 Aug 2009
Publisher: Child's Play International Ltd
Publication Country: Swindon, United Kingdom
Language: English
ISBN: 9781846432927
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Veronica Pacini-ketchabaw,Sylvia Kind,Laurie L. M. Kocher: Encounters with Materials in Early Childhood Education

Encounters with Materials in Early Childhood Education


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Encounters with Materials in Early Childhood Education rearticulates understandings of materials-blocks of clay, sheets of paper, brushes and paints-to formulate what happens when we think with materials and apply them to early childhood development and classrooms. The book develops ways of thinking about materials that are more sustainable and insightful than what most children in the Western world experience today through capitalist narratives. Through a series of ethnographic events and engagement with existing ideas of relationality in the visual arts, feminist ethics, science studies, philosophy, and anthropology, Encounters with Materials in Early Childhood Education highlights how materials can be conceptualized as active participants in early childhood education and generators of human insight. A variety of examples show how educators, young children, and researchers have engaged in thinking with materials in early years classrooms and explore what materials are capable of in their encounters with other materials and with children. Please visit the companion website at www.encounterswithmaterials.com for additional features, including interviews with the authors and the teachers featured in the book, videos and photographs of the classroom narratives described in these pages, and an ongoing blog of the authors' ethnographic notes.


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Author: Veronica Pacini-ketchabaw,Sylvia Kind,Laurie L. M. Kocher
Number of Pages: 104 pages
Published Date: 20 Sep 2016
Publisher: Taylor & Francis Ltd
Publication Country: London, United Kingdom
Language: English
ISBN: 9781138821460
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mercredi, août 30 2017

*FREE* On the Nature of Things pdf, epub, mobi

Lucretius,Frank O. Copley: On the Nature of Things

On the Nature of Things


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This great poem stands with Virgil's Aeneid as one of the vital and enduring achievements of Latin literature. Lost for more than a thousand years, its return to circulation in 1417 reintroduced dangerous ideas about the nature and meaning of existence and helped shape the modern world.

In this just-surreal enough take on the "school genre" of manga, a group of friends grapple with all sorts of unexpected situations in their daily lives as high schoolers. Several step by step On the Nature of Things free epub guitar making methods that make some of the more difficult processes easier and smoother in the shop. Known across the country for his appearance on "The Daily Show with Jon Stewart," Professor Richard Beeman is one of the nation's foremost experts on the United States Constitution. In this book, he has produced what every American should have: a compact, fully annotated copy of the Declaration of Independence, the Constitution and amendments, all in their entirety. A marvel of accessibility and erudition, the guide also features a history of the making of the Consittution with excerpts from "The Federalist Papers" and a look at crucial Supreme Court cases that reminds us that the meaning of many of the specific provisions of the Constitution has changed over time.


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Author: Lucretius,Frank O. Copley
Number of Pages: 208 pages
Published Date: 26 Sep 2011
Publisher: WW Norton & Co
Publication Country: New York, United States
Language: English
ISBN: 9780393341362
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Afternoon Tea download PDF

Jane Pettigrew,Jenni Davis: Afternoon Tea

Afternoon Tea


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One of the most civilised, sociable, and relaxing of customs is gathering around a beautifully laid table to take afternoon tea. Packed with gorgeous images, this informative guide contains details on every aspect of the formal tea, including how to make and serve it at its very best, the etiquette of tea-drinking, the correct china and silverware to use, how to host a tea party, and even how the tea gown evolved. Recipes for delicious teatime treats round out this must-have guide.


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Author: Jane Pettigrew,Jenni Davis
Number of Pages: 80 pages
Published Date: 30 Jul 2004
Publisher: The History Press Ltd
Publication Country: Stroud, United Kingdom
Language: English
ISBN: 9781841651439
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[FREE] Stig of the Dump download pdf, epub

Clive King,Tony Robinson: Stig of the Dump

Stig of the Dump


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Barney has found a wonderful place to play - the chalk-pit or rubbish dump near his granny's home. One day the ground gives way and Barney finds himself in a cave in the middle of the dump, and that's where he meets Stig. Stig is living wild and has a lot to learn from Barney, but equally he has a lot to teach him. They soon become friends, discover each other's ways and embark on a series of extraordinary adventures.


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Author: Clive King,Tony Robinson
Number of Pages: 3 pages
Published Date: 06 Mar 2003
Publisher: Penguin Books Ltd
Publication Country: United Kingdom
Language: English
ISBN: 9780141804033
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>FREE< The Way I Used to Be download pdf, epub

Amber Smith: The Way I Used to Be

The Way I Used to Be


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In the tradition of "Speak, "this extraordinary debut novel shares the unforgettable story of a young woman as she struggles to find strength in the aftermath of an assault. Eden was always good at being good. Starting high school didn t change who she was. But the night her brother s best friend rapes her, Eden s world capsizes. What was once simple, is now complex. What Eden once loved who she once loved she now hates. What she thought she knew to be true, is now lies. Nothing makes sense anymore, and she knows she s supposed to tell someone what happened but she can t. So she buries it instead. And she buries the way she used to be. Told in four parts freshman, sophomore, junior, and senior year this provocative debut reveals the deep cuts of trauma. But it also demonstrates one young woman s strength as she navigates the disappointment and unbearable pains of adolescence, of first love and first heartbreak, of friendships broken and rebuilt, and while learning to embrace a power of survival she never knew she had hidden within her heart."


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Author: Amber Smith
Number of Pages: 384 pages
Published Date: 22 Mar 2016
Publisher: Margaret K. McElderry Books
Publication Country: United States
Language: English
ISBN: 9781481449359
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Welcome to the Crystal Empire! download epub

Olivia London: Welcome to the Crystal Empire!

Welcome to the Crystal Empire!


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Twilight Sparkle tours the Crystal Empire. She attends the Crystal Faire, meets lots of Crystal Ponies and gets to stay in a special room in the castle with her very own library! Come explore the sparkling world of the Crystal Empire... This storybook includes a removable postcard to mail to your friends!


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Author: Olivia London
Number of Pages: 20 pages
Published Date: 10 Sep 2013
Publisher: LB Kids
Publication Country: United States
Language: English
ISBN: 9780316228244
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